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Haemophilia
Also spelled hemophilia, is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding. This results in people bleeding longer after an injury, easy bruising, and an increased risk of bleeding inside joints or the brain.
Symptoms:
- Nosebleeds
- Bruising, especially a large, lumpy bruise
- Bleeding for no known reason
- Blood in the urine or stool
- Bleeding that does not stop after getting a cut, having a tooth out, getting an injury to the mouth or having surgery
- Bleeding that does not stop after circumcision
- Bleeding into a joint, which can cause tightness, swelling and pain
Preliminary plan:
- General practitioner appointment
- Complete blood count (CBC)
- Reticulocyte count
- Urinalysis
- Blood group + RhD
- Stool analysis - Protozoans and Helminths (microscopy)
- Blood test:
- Latent iron-binding capacity
- Iron
- Vitamin B12 (cyanocobalamin)
- Transferrin
- Ferritin
- Folic acid (folates)
- Potassium Sodium Chlorine (K, Na, Cl) (blood)
- Urea (BUN)
- Creatinine
- Glucose
- Cholesterol
- Triglycerides
- Alkaline phosphatase (ALP)
- Alanine transaminase (ALT)
- Bilirubin (total, direct)
- Blood clotting test:
- Prothrombin ratio (PR) / International normalized ratio (INR)
- Fibrinogen
- Thrombin time
- aPTT
- Antithrombin III (AT-III)
- D-dimer
- Lupus anti-coagulant
- Protein C
- Protein S, free
- Coagulogram