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Porphyria
Refers to a group of disorders that result from a buildup of natural chemicals that produce porphyrin in your body. Porphyrins are essential for the function of hemoglobin — a protein in your red blood cells that links to porphyrin, binds iron, and carries oxygen to your organs and tissue.
Symptoms:
- Severe abdominal pain
- Swelling of the abdomen (abdominal distention)
- Pain in your chest, legs or back
- Constipation or diarrhea
- Vomiting
- Insomnia
- Heartbeat you can feel (palpitations)
- High blood pressure
- Anxiety or restlessness
- Seizures
- Mental changes, such as confusion, hallucinations, disorientation or paranoia
- Breathing problems
- Muscle pain, tingling, numbness, weakness or paralysis
- Red or brown urine
Preliminary plan:
- General practitioner appointment
- Complete blood count (CBC)
- Reticulocyte count
- Urinalysis
- Blood group + RhD
- Stool analysis - Protozoans and Helminths (microscopy)
- Blood test:
- Latent iron-binding capacity
- Iron
- Vitamin B12 (cyanocobalamin)
- Transferrin
- Ferritin
- Folic acid (folates)
- Potassium Sodium Chlorine (K, Na, Cl) (blood)
- Urea (BUN)
- Creatinine
- Glucose
- Cholesterol
- Triglycerides
- Alkaline phosphatase (ALP)
- Alanine transaminase (ALT)
- Bilirubin (total, direct)
- Blood clotting test:
- Prothrombin ratio (PR) / International normalized ratio (INR)
- Fibrinogen
- Thrombin time
- aPTT
- Antithrombin III (AT-III)
- D-dimer
- Lupus anti-coagulant
- Protein C
- Protein S, free
- Coagulogram